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While some lean mass loss inevitably occurs during significant weight reduction, the rate is typically 20-25% of total weight lost on tirzepatide compared to 30-40% with diet-only approaches

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4 The symptoms and signs of herpes zoster ophthalmicus are the same as for shingles affecting other areas, but patients present with a periorbital distribution of the rash, and all parts of the eye innervated by the ophthalmic branch of the trigeminal nerve can be affected (Figure 3)