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There’s reishi , found in a 2023 animal study to promote an “enhanced disease-defending [immune] system”;59 and chaga , which appears to have “anticancer, antioxidant, anti-diabetic, anti-inflammatory, antimicrobial, and immunomodulating properties,” per a 2024 review.60 (The blend once contained lion’s mane , which also has immunoregulatory and antimicrobial qualities, but it has been nixed in the reformulation).61 Thing is, dosing is a problem