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Glutathione lotions and creams are popular in skincare, but their results vary

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Using SH-SY5Y cells exposed to high glucose concentrations to induce hyperglycemia, disruptions in glucose sensing leads to activation of the phosphorylated protein kinase B (pAkt)/GSK-3β signaling pathway, and increased expression of BACE and Aβ42, an effect that can be reversed via pretreatment with melatonin [62]