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Apart from ligand selectivity, huge differences in downstream G protein signaling are present between CCK1R and CCK2R

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Let’s consider the numbers: If the current increase in the number of Peyronie’s indications among younger men maintains currently evaluated levels (not maintaining the current 20% growth clip) The under-45 crowd numbers are combined with the new slightly higher percentage of men with PD 45 years and older We add a nominal allowable percentage (3%) for new PD diagnosis triggered by accidents and direct penile injury, The result indicates 25-30% of adult US males could be facing consequences of penile fibrosis and plaques within the next 20 years