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Sometimes, the root cause is relatively easy to eliminate such as discontinuing the stomach acid-suppressing drugs in case of B12 deficiency or switching from Phenytoin to some other ant-seizure drug in case of folate deficiency

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This observation is in line with (a) decreased plasma GSH levels in women who underwent surgical menopause (Kaur et al., 2017), and (b) decreased serum tGSH levels in post- relative to pre-menopausal women (Ramírez-Expósito et al., 2014)