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Synthesis and Endotoxin Considerations Research-grade BPC-157 peptide should be synthesized using solid-phase peptide synthesis (SPPS) under controlled GMP-aligned conditions and tested for endotoxin contamination prior to release

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Finally, post-reperfusion therapy using antioxidants/anti-inflammatory agents have been investigated in clinical trials with mixed outcomes, indicating a need for further research in this area to better understand cerebroprotection targets in this stage (Savitz et al., 2025