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Most arsenic absorbed into the body is converted by the liver to less toxic methylated form that is efficiently excreted in the urine

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Clinical research on DIM typically uses doses between 100mg and 300mg per day , though the form of DIM matters.30 Standard (crystalline) DIM: Often used at higher doses (e.g., 200–300mg) due to lower bioavailability BioResponse DIM (BR-DIM): A more bioavailable form used in many studies, often at doses around 100–200mg per day, which may achieve similar effects to higher doses of standard DIM5 That said, higher doses don’t necessarily lead to better results