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ABSTRACT A Brief Review of Immunologic Reactions Lymphocyte Surface Molecules Antigen Presentation On Mhc Molecules T And B Cell Responses Killer (K) And Natural Killer (Nk) Cells Self-Non-Self Discrimination The Syndromes of Thyroid Autoimmunity The Antigens in AUTOIMMUNE THYROID DISEASE Immune Reactions in Autoimmune thyroid disease Cell-Mediated Immunity In Autoimmune Thyroid Disease Immune Complexes K And Nk Cell Responses Cytokines SUMMARY EXPERIMENTAL THYROIDITIS IN ANIMALS Possible Explanations for Autoimmunity Abnormal Exposure To Thyroid Antigens And The Effects Of Pregnancy Abnormal Antigens Cross-Reacting Antigens Virus Infection Lymphocyte Mutation And Oligoclonality Genetic Predisposition Co-Occurrence Of Autoimmune Diseases Immunoregulation: Phenomena And Mechanisms Anti-Idiotype Antibodies De Novo Expression Of Class Ii Antigens On Thyroid Cells ENVIRONMENTAL FACTORS NORMAL AUTOIMMUNITY Effect of Antithyroid Drugs on the Immune Response THYROIDITIS, MYXEDEMA, AND GRAVES' DISEASE AS AUTOIMMUNE DISEASES Idiopathic Myxedema Graves' Disease RELATION TO OTHER DISEASES : Thyroid Cancer Transient Thyrotoxicosis, Painless Thyroiditis, Postpartum Thyroiditis, And Related Syndromes Focal Thyroiditis Riedel’s Thyroiditis And Ig4 Disease Other Problems REFERENCES Review Autoimmune Polyglandular Syndromes.[Endotext

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