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Patients with vestibular complaints require evaluation with an electronystagmogram (ENG), and those with complete facial nerve paralysis require electrophysiologic testing (EMG, ENoG) in order to assess candidacy for facial nerve decompression

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Animal research has examined DSIP's effects on stress hormone regulation, including studies proposing effects on ACTH and broader neuroendocrine stress responses, forming part of the basis for research interest in DSIP beyond sleep specifically