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At high percentage oxyhaemoglobin levels, where the R-configuration of haemoglobin prevails over the T-configuration, the rate of oxidation is lower

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Besides, the similarities are also reflected in their pathogenic mechanisms, such as the secretion of pro-inflammatory and pro-fibrotic factors, oxidative stress, mitochondrial dysfunction, and loss of renoprotective factors (O’Sullivan et al., 2017)