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We evaluated total ROS levels in three patients from the family population-omics profiling (fPOP) cohort (66), who presented with chronic symptoms (Fig

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α-Melanocyte stimulating hormone (α-MSH) was purchased from TOCRIS (Bristol, UK), and apoptosis detection kit using FITC (fluorescein isothiocyanate)-labeled annexin V was purchased from BD Biosciences (Bedford, MA, USA)