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Mechanistically, FSP1 functions as an NAD(P)H-dependent oxidoreductase that re-generates lipophilic RTAs, which reduce lipid-derived peroxyl radicals to inhibit the propagation of lipid peroxidation [[50], [51], [52],92]

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This transporter is well-characterized in terms of its structure and function, with a number of drugs decreasing thiamine transport through SLC19A3 (109)