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Reactive oxygen and nitrogen species are generated by activated microglia, infiltrating macrophages, and dysfunctional mitochondria within inflammatory lesions, where they contribute to demyelination, axonal injury, and neurodegeneration (Ohl et al., 2016)
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It has not been evaluated by bodies like the United States Food and Drug Administration (FDA) or comparable international agencies, leading to a significant gap in understanding its safety for human use
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