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Millilitres:10ml
The highest concentrations in both brain and plasma of mitragynine (administered po in C57BL/6J mice) 7OH and MP (metabolites formed from mitragynine po) matched the antinociceptive peak effect in C57BL/6J mice at 20 min generally (See Figure 3 for concentrations observed and Figure S1A,C for antinociception time course)
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