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Reactive oxygen species (Ros-Induced) Ros release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

L-Glutathione Tablets

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Trials should co-primary (1) mechanistic change (e.g., Prx cycling, 2-OH-E⁺, LIP) and (2) clinical improvement (function, organ scores), preventing the common trap of “ROS lowering without benefit” (Guideline 2022)