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The two major groups within Burkholderia are the Burkholderia cepacia complex (BCC) and the Burkholderia pseudomallei complex (BPC), with ongoing reclassifications leading to the emergence of genera such as Paraburkholderia and Caballeronia
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The high-affinity copper importer CTR1 (SLC31A1) functions as a redox sensor in endothelial cells, facilitating VEGFR2 activation and enhancing VEGF-driven neovascularization, while the copper-exporting ATPase ATP7A prevents autophagic degradation of VEGFR2, thereby sustaining VEGF signaling 190,191
![PDF] Kinetic Mechanism and Molecular Properties of Glutathione Reductase](https://figures.semanticscholar.org/86e0c3c8c13578b78a6eae1f4d6a473e325ce3d3/4-Figure1-1.png)
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