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⛔Contraindications •No formal contraindications established (no human studies) •Theoretical concern for individuals with NNMT-dependent cancers •Theoretical concern for pregnancy/lactation (no reproductive toxicity data) ⚠️Drug Interactions •No drug interaction studies have been conducted •Theoretical interaction with medications affecting methylation pathways •Theoretical interaction with NAD+ precursors (NMN, NR) -- unstudied Community-Reported Side Effects See which side effects community members report most frequently

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10.1016/j.ejphar.2015.05.019 22 Cattani-CavalieriI.LiY.MargolisJ.BogardA.RoosanM