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examined the susceptibility of different monocyte subsets to H 2 O 2 -induced cytotoxicity, and reported that CD16 + monocytes had increased cell death in response to H 2 O 2 as well as decreased GPx1 expression [46] (knockdown of GPx1 in CD16 − monocytes recapitulated the phenotype)
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Furthermore, excessive iron deposition in specific brain areas contributes to AD pathology (Moon et al., 2016)
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