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As a result, β -TCP coating altered Mg’s detrimental osteo-immunomodulatory properties and induced a beneficial switch to the M2 macrophage phenotype, modulating inflammation by suppressing the TLRs pathway, and enhancing osteogenesis after activation of the bone morphogenetic protein 2 (BMP2) signaling pathway
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We have previously shown that estrogen-induced transcription is triggered by LSD1-catalyzed demethylation of lysine 9 in histone H3 (H3K9), which is activated by the binding of liganded estrogen receptor to the enhancers of target genes 140
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