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The most representative type of microglia during demyelination expressed CD11b + /CD45 low (CD, cluster of differentiation) and displayed a high ex vivo phagocytic activity accompanied by up-regulation of several phagocytic receptors such as Trem2b, FcγR II/III, CD36, and Tim-3 (Voss et al., 2012) suggesting that phagocytosis is one of the most prominent features of microglia in the cuprizone model

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