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In addition, the Ub-independent pathway involves some mitophagy receptors localised to the OMM, such as FUN14 domain containing 1 (FUNDC1), B cell lymphoma-2 (BCL-2), adenovirus E1B 19 kDa interacting protein 3 (BNIP3), Nip3-like protein X (NIX), BCL-2-like protein 13 (BCL2L13) and FK506 binding protein 8 (FKBP8) [54–56]
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Methylene blue was the first fully synthetic drug to be used in medicine for the treatment of malaria parasites 2