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Dawlaty et al., 2013), and 100 μM vitamin C is sufficient to increase 5hmC by up to ∼4-fold above basal levels in ESCs within 24hrs of treatment, with even larger effects on the levels of 5fC (10-fold increase) and 5caC (20-fold increase) (Yin et al., 2013)

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[DOI] [PubMed] [Google Scholar] 33.Zhang YF, Qiao W, Feng H, Jiang K, Yang J, Zhou T, Zhang Y