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Probiotic therapy of COVID-19 patients with a combination of nine different lactobacilli strains (as daily dose), showed significant alterations in gut microbiota, partial restoration of pulmonary dysfunction as well as intestinal dysbiosis

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The main disadvantage of the microbiological method, however, is its low specificity as it measures a variety of cobalamin analogs that are not necessarily biologically active (Sobczynska-Malefora et al., 2021)