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Lactate synthesis, as an electron sink to regenerate NAD + , is both temporary and limited because the dead-end metabolite is trapped in the cytosol due to the lack of MCT1 plasma membrane monocarboxylate transporters, explaining the low level of glucose-dependent lactate output from β-cells (Pullen et al., 2012

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Iron: Research has shown a possible association between fibromyalgia and decreased ferritin levels