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They specifically investigated the in vitro induction of eryptosis on healthy RBCs exposed to septic plasma at different time points and evaluated the relationship between eryptosis percentage and Endotoxin Activity Assay (EAA) levels, mortality, and other biological markers of inflammation and oxidative stress [383]
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Peroxynitrite is a potent oxidizing agent that can cause lipid peroxidation, protein tyrosine nitration, DNA damage, and cell death
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