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The drug-free neutrally charged peptide, containing a cationic peptide guanidinium-functionalized poly(L-lysine) and a pH-sensitive peptide poly(ethylene glycol)-b-poly(ʟ-lysine)-graft-cyclohexene-1,2-dicarboxylic anhydride, exhibited similar efficacy against resistant MCF-7/ADR cells and MCF-7 cells in vitro (Yang et al., 2022)
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In turn, the rhythm of the central clock is reinforced and enhanced by relying on and integrating feedback signals from the peripheral clocks
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